2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-

Modify Date: 2024-01-09 20:26:55

2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]- Structure
2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]- structure
Common Name 2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
CAS Number 2885-39-4 Molecular Weight 339.38400
Density 1.24g/cm3 Boiling Point 529.4ºC at 760mmHg
Molecular Formula C17H25NO6 Melting Point N/A
MSDS N/A Flash Point 274ºC

 Names

Name 2,6-Piperidinedione, 4-[2-[5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-, [1S-[1.α.(S*),3.β.,5.β.]]
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 529.4ºC at 760mmHg
Molecular Formula C17H25NO6
Molecular Weight 339.38400
Flash Point 274ºC
Exact Mass 339.16800
PSA 109.77000
LogP 1.05600

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA5075000
CHEMICAL NAME :
Glutarimide, 3-(2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexy l)ethyl)-, 5-acetate
CAS REGISTRY NUMBER :
2885-39-4
LAST UPDATED :
199009
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C17-H25-N-O6
MOLECULAR WEIGHT :
339.43
WISWESSER LINE NOTATION :
T6VMVTJ EYQ1- BL6VTJ DOV1 D1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
158 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
170 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
190 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
920 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human HeLa cell
DOSE/DURATION :
1 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,205,1965

 Synonyms

AXM
Antibiotic from streptomyces albulus
Streptovitacin E 73
Cycloheximide,4-acetoxy-(E-B)
Acetyloxycycloheximide
Antibiotic SF-2441
Acetoxycycloheximide
Cycloheximide,acetoxy