Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

Modify Date: 2024-01-04 17:35:49

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure
Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate structure
Common Name Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate
CAS Number 289042-11-1 Molecular Weight 381.422
Density 1.3±0.1 g/cm3 Boiling Point 552.0±60.0 °C at 760 mmHg
Molecular Formula C17H20FN3O4S Melting Point N/A
MSDS N/A Flash Point 287.6±32.9 °C

 Names

Name Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 552.0±60.0 °C at 760 mmHg
Molecular Formula C17H20FN3O4S
Molecular Weight 381.422
Flash Point 287.6±32.9 °C
Exact Mass 381.115845
PSA 97.84000
LogP 1.59
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.557

 Safety Information

HS Code 2935009090

 Synthetic Route

~93%

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure

Methyl4-(4-fluo...

CAS#:289042-11-1

Literature: WO2007/74391 A2, ; Page/Page column 16 ;

~77%

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure

Methyl4-(4-fluo...

CAS#:289042-11-1

Literature: WO2004/103977 A2, ; Page 22-23 ;

~89%

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure

Methyl4-(4-fluo...

CAS#:289042-11-1

Literature: WO2008/59519 A2, ; Page/Page column 8; 16; 20-21 ;

~%

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure

Methyl4-(4-fluo...

CAS#:289042-11-1

Literature: US2004/49036 A1, ; Page 3 ;

~%

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure

Methyl4-(4-fluo...

CAS#:289042-11-1

Literature: US2003/45718 A1, ;

~%

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate Structure

Methyl4-(4-fluo...

CAS#:289042-11-1

Literature: EP1849765 A1, ; Page/Page column 15-16 ;

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

MFCD08235142
Z-6
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-carboxylate
Rosuvastatin intermediate R-1-1
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinecarboxylate
5-Pyrimidinecarboxylic acid, 4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, methyl ester
ZD-1
methyl 4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidine-5-carboxylate
Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate