WM-586

Modify Date: 2024-09-27 20:53:17

WM-586 structure	Common Name	WM-586
	CAS Number	2894832-05-2	Molecular Weight	467.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₀F₃N₅O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of WM-586

WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR5 and MYC interaction with the IC50 of 101 nM in HTRF assay[1].

Name	WM-586

Description	WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR5 and MYC interaction with the IC50 of 101 nM in HTRF assay[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	IC50: 101 nM (WDR5 and MYC interaction)[1]
References	[1]. Ding J, et al. Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chem Biol. 2023 Jan 20;18(1):34-40.

Molecular Formula	C₂₀H₂₀F₃N₅O₃S
Molecular Weight	467.46