PG 116800

Modify Date: 2024-09-03 12:19:04

PG 116800 Structure
PG 116800 structure
Common Name PG 116800
CAS Number 291533-11-4 Molecular Weight 501.55200
Density N/A Boiling Point N/A
Molecular Formula C24H27N3O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PG 116800


PG 116800 (PG 530742) is an orally avtive MMP inhibitor. PG 116800 has high affinity for MMP-2, -3, -8, -9, -13, and -14, while having substantially lower affinity for MMP-1 and -7. PG 116800 can be used for knee osteoarthritis research[1].

 Names

Name 2-[[4-[(4-methoxybenzoyl)amino]phenyl]sulfonylamino]-5-morpholin-4-ylpent-3-ynoic acid

 PG 116800 Biological Activity

Description PG 116800 (PG 530742) is an orally avtive MMP inhibitor. PG 116800 has high affinity for MMP-2, -3, -8, -9, -13, and -14, while having substantially lower affinity for MMP-1 and -7. PG 116800 can be used for knee osteoarthritis research[1].
Related Catalog
References

[1]. Piotr Krzeski, et al. Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. Arthritis Res Ther. 2007;9(5):R109.  

 Chemical & Physical Properties

Molecular Formula C24H27N3O7S
Molecular Weight 501.55200
Exact Mass 501.15700
PSA 146.14000
LogP 3.19830
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