2-(Trimethylsilyl)ethanol

Modify Date: 2024-01-02 13:07:00

2-(Trimethylsilyl)ethanol Structure
2-(Trimethylsilyl)ethanol structure
 Common Name 2-(Trimethylsilyl)ethanol
CAS Number 2916-68-9 Molecular Weight 118.250
Density 0.825 Boiling Point 145.0±13.0 °C at 760 mmHg
Molecular Formula C5H14OSi Melting Point 0ºC
MSDS USA Flash Point 50.6±0.0 °C
Symbol GHS02
GHS02		 Signal Word Warning

 Names

Name 2-(Trimethylsilyl)ethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.825
Boiling Point 145.0±13.0 °C at 760 mmHg
Melting Point 0ºC
Molecular Formula C5H14OSi
Molecular Weight 118.250
Flash Point 50.6±0.0 °C
Exact Mass 118.081390
PSA 20.23000
LogP 1.36
Vapour Pressure 2.0±0.6 mmHg at 25°C
Index of Refraction 1.406
Storage condition 0-6°C
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM5480000
CHEMICAL NAME :
Ethanol, 2-(trimethylsilyl)-
CAS REGISTRY NUMBER :
2916-68-9
BEILSTEIN REFERENCE NO. :
1732034
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H14-O-Si
MOLECULAR WEIGHT :
118.28
WISWESSER LINE NOTATION :
Q2-SI-1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1122 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 229,1011,1976

 Safety Information

Symbol GHS02
GHS02
Signal Word Warning
Hazard Statements H226
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R10;R36/37/38
Safety Phrases S16-S37/39-S26
RIDADR UN 1987 3/PG 3
WGK Germany 3
RTECS KM5480000
Packaging Group III
Hazard Class 3
HS Code 29310095

 Synthetic Route

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Articles8

More Articles
Effects of charge, volume, and surface on binding of inhibitor and substrate moieties to acetylcholinesterase.

J. Med. Chem. 28(9) , 1309-13, (1985)

Reversible inhibitors for acetylcholinesterase, AcChE, have been studied. Sterically similar alcohols with tetra-substituted uncharged beta groups, (CH3)3SiCH2CH2OH (I), (CH3)3CCH2CH2OH (IA), and CH3S...

Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines: application in the construction of the communesin ring system.

Org. Lett. 8 , 3995, (2006)

A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is described. This methodology has been exploited in the rapid...

Silicon compounds as substrates and inhibitors of acetylcholinesterase.

Biochim. Biophys. Acta 791(2) , 278-80, (1984)

Several trimethylsilyl derivatives were found to be ligands of acetylcholinesterase (acetylcholine acetylhydrolase, EC 3.1.1.7): trimethylsilylethyl acetate (III) and trimethylsilylmethyl acetate (V) ...

 Synonyms

2-Hydroxyethyltrimethylsilane
Silane, (2-hydroxyethyl)trimethyl-
(2-Hydroxyethyl)Trimethylsilane
2-Trimethylsilylethanol
2-(Trimethylsilyl)ethanal
2-(trimethylsilyl)ethan-1-ol
MFCD00002825
trimethsilylethanol
Ethanol, 2-(trimethylsilyl)-
trimethylsilyl ethanol
2-(Trimethylsilyl)ethanol
2-TMS-ethanol
Ethanol, 2- (trimethylsilyl)-
2-Trimethylsilanyl-ethanol
EINECS 220-844-5
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