Anti-inflammatory agent 55

Modify Date: 2024-07-17 11:16:36

Anti-inflammatory agent 55 structure	Common Name	Anti-inflammatory agent 55
	CAS Number	2924156-51-2	Molecular Weight	373.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₅N₃O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anti-inflammatory agent 55

Anti-inflammatory agent 55 (compound 9j) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC50: 0.8 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model[1].

Name	Anti-inflammatory agent 55

Description	Anti-inflammatory agent 55 (compound 9j) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC50: 0.8 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology
References	[1]. Cui E, et al. Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents. J Nat Prod. 2023 Aug 25;86(8):1950-1959..

Molecular Formula	C₁₇H₁₅N₃O₇
Molecular Weight	373.32

Anti-inflammatory agent 55

Use of Anti-inflammatory agent 55

Names

Anti-inflammatory agent 55 Biological Activity

Chemical & Physical Properties