6-(Dimethylamino)-4,4-diphenyl-3-heptanone

Modify Date: 2024-02-03 15:28:08

6-(Dimethylamino)-4,4-diphenyl-3-heptanone Structure
6-(Dimethylamino)-4,4-diphenyl-3-heptanone structure
Common Name 6-(Dimethylamino)-4,4-diphenyl-3-heptanone
CAS Number 297-88-1 Molecular Weight 309.44500
Density N/A Boiling Point N/A
Molecular Formula C21H27NO Melting Point 99-100ºC
MSDS N/A Flash Point N/A

 Names

Name 6-(Dimethylamino)-4,4-diphenyl-3-heptanone

 Chemical & Physical Properties

Melting Point 99-100ºC
Molecular Formula C21H27NO
Molecular Weight 309.44500
Exact Mass 309.20900
PSA 20.31000
LogP 4.29200

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MJ5960000
CHEMICAL NAME :
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (+-)-
CAS REGISTRY NUMBER :
297-88-1
LAST UPDATED :
199806
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C21-H27-N-O
MOLECULAR WEIGHT :
309.49
WISWESSER LINE NOTATION :
2VXR&R&1Y1&N1&1 -(+-)

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
95 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
240 mg/kg
SEX/DURATION :
female 7 day(s) pre-mating - 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - other neonatal measures or effects Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
12500 ug/kg
SEX/DURATION :
lactating female 5 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - biochemical and metabolic

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - rat Testis
DOSE/DURATION :
10 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,123,1978

 Safety Information

RIDADR UN 1544
Packaging Group III
Hazard Class 6.1(b)