Luteolin-7-O-glucuronide

Modify Date: 2024-01-02 16:59:40

Luteolin-7-O-glucuronide Structure
Luteolin-7-O-glucuronide structure
Common Name Luteolin-7-O-glucuronide
CAS Number 29741-10-4 Molecular Weight 462.360
Density 1.8±0.1 g/cm3 Boiling Point 892.5±65.0 °C at 760 mmHg
Molecular Formula C21H18O12 Melting Point 242-244℃
MSDS N/A Flash Point 315.2±27.8 °C

 Use of Luteolin-7-O-glucuronide


Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

 Names

Name luteolin 7-O-β-D-glucosiduronic acid
Synonym More Synonyms

 Luteolin-7-O-glucuronide Biological Activity

Description Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
Related Catalog
Target

MMP-1:17.63 μM (IC50)

MMP-3:7.99 μM (IC50)

MMP-8:11.42 μM (IC50)

MMP-9:12.85 μM (IC50)

MMP13:0.03 μM (IC50)

References

[1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911.

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 892.5±65.0 °C at 760 mmHg
Melting Point 242-244℃
Molecular Formula C21H18O12
Molecular Weight 462.360
Flash Point 315.2±27.8 °C
Exact Mass 462.079834
PSA 207.35000
LogP -0.25
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.764
Storage condition ?20°C

 Synonyms

(2S,3S,4S,5R)-6-[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
luteolin 7-O-beta-D-glucosiduronic acid
Luteolin-7-glucuronide
2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranuronosyloxy)-5-hydroxy-
Luteolin 7-O-glucuronide
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Price: ¥1100/5 mg

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