Aica ribonucleotide

Modify Date: 2024-01-02 21:36:02

Aica ribonucleotide Structure
Aica ribonucleotide structure
Common Name Aica ribonucleotide
CAS Number 3031-94-5 Molecular Weight 338.21
Density 2.3g/cm3 Boiling Point 845.3ºC at 760 mmHg
Molecular Formula C9H15N4O8P Melting Point 198-202ºC dec.
MSDS USA Flash Point 465ºC

 Use of Aica ribonucleotide


AICA-riboside, 5′-phosphate (AICAR-5'-MP) is a 5'-phosphorylated analogue of AICAR. AICAR is an adenosine analog and a AMPK activator. [1].

 Names

Name 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate
Synonym More Synonyms

 Aica ribonucleotide Biological Activity

Description AICA-riboside, 5′-phosphate (AICAR-5'-MP) is a 5'-phosphorylated analogue of AICAR. AICAR is an adenosine analog and a AMPK activator. [1].
Related Catalog

 Chemical & Physical Properties

Density 2.3g/cm3
Boiling Point 845.3ºC at 760 mmHg
Melting Point 198-202ºC dec.
Molecular Formula C9H15N4O8P
Molecular Weight 338.21
Flash Point 465ºC
Exact Mass 338.06300
PSA 213.19000
Index of Refraction 1.831
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29349990

 Synthetic Route

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Aica ribonucleotide Structure

Aica ribonucleotide

CAS#:3031-94-5

Literature: Federation Proc., , vol. 12, p. 211

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Aica ribonucleotide Structure

Aica ribonucleotide

CAS#:3031-94-5

Literature: Journal of Biological Chemistry, , vol. 228, p. 201,207

 Articles54

More Articles
In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.

Br. J. Cancer 111(8) , 1562-71, (2014)

The increasing usage of statins (the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) has revealed a number of unexpected beneficial effects, including a reduction in cancer risk.We investi...

Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase.

Biochemistry 52(37) , 6559-67, (2013)

N(5)-CAIR synthetase, an essential enzyme in microorganisms, converts 5-aminoimidazole ribonucleotide (AIR) and bicarbonate to N(5)-CAIR with the aid of ATP. Previous X-ray crystallographic analyses o...

Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages.

PLoS ONE 7(12) , e53101, (2012)

Genistein, the major isoflavone in soybean, was recently reported to exert beneficial effects in metabolic disorders and inflammatory diseases. In the present study, we investigated the effects and me...

 Synonyms

EINECS 221-212-1
MFCD00057264
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-β-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
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