2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol

Modify Date: 2024-01-10 05:59:05

2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol Structure
2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol structure
Common Name 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol
CAS Number 31173-14-5 Molecular Weight 247.25700
Density 1.166g/cm3 Boiling Point 317.2ºC at 760mmHg
Molecular Formula C12H16F3NO Melting Point N/A
MSDS N/A Flash Point 145.6ºC

 Names

Name 2-({1-[3-(Trifluoromethyl)phenyl]-2-propanyl}amino)ethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.166g/cm3
Boiling Point 317.2ºC at 760mmHg
Molecular Formula C12H16F3NO
Molecular Weight 247.25700
Flash Point 145.6ºC
Exact Mass 247.11800
PSA 32.26000
LogP 2.60920
Index of Refraction 1.475

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL8235000
CHEMICAL NAME :
Ethanol, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-
CAS REGISTRY NUMBER :
31173-14-5
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H16-F3-N-O
MOLECULAR WEIGHT :
247.29
WISWESSER LINE NOTATION :
Q2M1Y1&R CXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
184 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970

 Synthetic Route

~44%

2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol Structure

2-[[1-methyl-2-...

CAS#:31173-14-5

Literature: Caldirola, P.; Zandberg, P.; Mannhold, R.; Timmerman, H. European Journal of Medicinal Chemistry, 1993 , vol. 28, # 7-8 p. 555 - 568

~%

2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol Structure

2-[[1-methyl-2-...

CAS#:31173-14-5

Literature: Science Union et Cie. Patent: FR1517587 , 1968 ; Chem.Abstr., 1969 , vol. 70, # 106229

 Synonyms

1-(3-trifluoromethyl phenyl)-2-(2-hydroxyethyl)-amino propane
2-({1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl}amino)ethanol
4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-pyridin-3-ylamine
1-(3-Amino-4-pyridyl)-4-(m-trifluoromethylphenyl)piperazine
1-(3-Trifluormethylphenyl)-4-(3-aminopyrid-4-yl)-piperazin
4-(m-Trifluoromethylphenyl)-1-(3-amino-4-pyridyl)piperazine
N-{2-[1-methyl-2-(3-trifluoromethyl)phenyl]ethyl}aminoethanol