l-α-Hexachlorocyclohexane

Modify Date: 2024-01-01 17:29:52

l-α-Hexachlorocyclohexane Structure
l-α-Hexachlorocyclohexane structure
Common Name l-α-Hexachlorocyclohexane
CAS Number 319-84-6 Molecular Weight 290.830
Density 1.6±0.1 g/cm3 Boiling Point 288.0±0.0 °C at 760 mmHg
Molecular Formula C6H6Cl6 Melting Point 156-161 °C(lit.)
MSDS Chinese USA Flash Point 157.5±23.9 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

 Names

Name α-hexachlorocyclohexane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 288.0±0.0 °C at 760 mmHg
Melting Point 156-161 °C(lit.)
Molecular Formula C6H6Cl6
Molecular Weight 290.830
Flash Point 157.5±23.9 °C
Exact Mass 287.860077
LogP 3.99
Appearance of Characters Solid | White
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.533
Storage condition APPROX 4°C
Stability Stable. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GV3500000
CHEMICAL NAME :
Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-isomer
CAS REGISTRY NUMBER :
319-84-6
BEILSTEIN REFERENCE NO. :
3195880
LAST UPDATED :
199710
DATA ITEMS CITED :
38
MOLECULAR FORMULA :
C6-H6-Cl6
MOLECULAR WEIGHT :
290.82
WISWESSER LINE NOTATION :
L6TJ AG BG CG DG EG FG ALPHA

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
14 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
177 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
78 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18 mg/kg/15D-C
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
36 mg/kg/30D-C
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8736 mg/kg/26W-C
TOXIC EFFECTS :
Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 gm/kg/48W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Liver - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 gm/kg/24W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 gm/kg/24W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11040 mg/kg/86W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13020 mg/kg/92W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12960 mg/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8820 mg/kg/21W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5040 mg/kg/24W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
TYPE OF TEST :
Morphological transformation
TYPE OF TEST :
Unscheduled DNA synthesis

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
756 mg/kg/3W
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,1245,1975 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,195,1979 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.5 mg/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.5 mg/m3;Skin JAN 1993 OEL-DENMARK:.TWA 5 mg/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.5 mg/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-FINLAND:TWA 0.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-FRANCE:TWA 0.5 mg/m3;Skin JAN 1993 OEL-GERMANY:TWA 0.5 mg/m3;Skin JAN 1993 OEL-HUNGARY:TWA 0.5 mg/m3;STEL 0.1 mg/m3;Skin JAN 1993 OEL-RUSSIA:STEL 0.05 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.5 mg/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.5 mg/m3;STEL 1.5 mg/m3;Skin JAN 1993

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301-H312-H351-H410
Precautionary Statements P273-P280-P301 + P310-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes F;T;N
Risk Phrases R21;R25;R40;R23/24/25;R50/53
Safety Phrases S22;S45;S60;S61;S36/S37
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS GV3500000
Packaging Group III

 Articles34

More Articles
Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil.

Environ. Int. 40 , 162-9, (2012)

Persistent organic pollutants (POPs) present in the living environment are thought to have detrimental health effects on the population, with pregnant women and the developing foetus being at highest ...

Levels of organochlorine contaminants in organic and conventional cheeses and their impact on the health of consumers: an independent study in the Canary Islands (Spain).

Food Chem. Toxicol. 50(12) , 4325-32, (2012)

In the present work we have evaluated the levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) in 61 commercially available brands of cheese (54 conventional and 7 organic) ...

Temporal trends of selected POPs and the potential influence of climate variability in a Greenland ringed seal population.

Environ. Sci. Process. Impacts 15(9) , 1706-16, (2013)

Temporal trends of selected POPs (PCB-52 and 153, p,p'-DDE, HCB, α- and β-HCH) in blubber of ringed seals (Pusa hispida) collected from the early 1990s to 2010 from central West Greenland were studied...

 Synonyms

MFCD00135946
a-Benzenehexachloride
α-HCH
Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1α,2α,3β,4α,5β,6β)-
Benzenehexachloride a-Isomer
a-Hexachlorane
a-Hexachlorocyclohexane
α-Hexachlorocyclohexane (α-HCH)
1,2,3,4,5,6-Hexachlorocyclohexane a-Isomer
α-1,2,3,4,5,6-Hexachlorocyclohexane
levo-α-Hexachlorocyclohexane
alpha-hexachlorocyclohexane
α-Hexachloran
a-HCH
α-Benzenehexachloride
EINECS 206-270-8
(1R,2R,3R,4R,5S,6S)-1,2,3,4,5,6-Hexachlorocyclohexane
a-Benzohexachloride
a-Benzene hexachloride
a-Hexachlorcyclohexane
Octanoic acid,1-chloroethyl ester
a-1,2,3,4,5,6-Hexachlorocyclohexane
a-BHC
a-Hexachloran
a-Lindane
α-Hexachlorocyclohexane
α-Lindane
Top Suppliers:I want be here



Get all suppliers and price by the below link:

l-α-Hexachlorocyclohexane suppliers

l-α-Hexachlorocyclohexane price