(Trimethylsilyl)methanol

Modify Date: 2024-01-02 18:02:25

(Trimethylsilyl)methanol Structure
(Trimethylsilyl)methanol structure
Common Name (Trimethylsilyl)methanol
CAS Number 3219-63-4 Molecular Weight 104.223
Density 0.8±0.1 g/cm3 Boiling Point 119.8±13.0 °C at 760 mmHg
Molecular Formula C4H12OSi Melting Point <0ºC
MSDS Chinese USA Flash Point 31.1±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Names

Name trimethylsilylmethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 119.8±13.0 °C at 760 mmHg
Melting Point <0ºC
Molecular Formula C4H12OSi
Molecular Weight 104.223
Flash Point 31.1±0.0 °C
Exact Mass 104.065742
PSA 20.23000
LogP 0.83
Vapour Pressure 7.6±0.4 mmHg at 25°C
Index of Refraction 1.398
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PC4100000
CHEMICAL NAME :
Methanol, (trimethylsilyl)-
CAS REGISTRY NUMBER :
3219-63-4
BEILSTEIN REFERENCE NO. :
1731486
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H12-O-Si
MOLECULAR WEIGHT :
104.25
WISWESSER LINE NOTATION :
Q1-SI-1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1080 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 229,1011,1976

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R10
Safety Phrases S26-S36
RIDADR UN 1987 3/PG 3
WGK Germany 3
RTECS PC4100000
Packaging Group III
Hazard Class 3
HS Code 2931900090

 Synthetic Route

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Articles7

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Enantioselective esterification of racemic naproxen by lipases in organic solvent.

Enzyme Microb. Technol. 16(4) , 328-33, (1994)

Enantioselective esterification of naproxen, 2-(6-methoxy-2-naphthyl) propionic acid, was attempted by lipases in nearly anhydrous isooctane. The nature of the alcohol affects the reactivity and enant...

Efficient kinetic resolution of (R,S)-1-trimethylsilylethanol via lipase-mediated enantioselective acylation in ionic liquids.

Chirality 18(10) , 814-21, (2006)

Efficient enantioselective acylation of (R,S)-1-trimethylsilylethanol {(R,S)-1-TMSE} with vinyl acetate catalyzed by immobilized lipase from Candida antarctica B (i.e., Novozym 435) was successfully c...

E. Vedejs, G.R. Martinez

J. Am. Chem. Soc. 101 , 6452, (1979)

 Synonyms

(Trimethylsilyl)methanol
1-TRIMETHYLSILYLMETHANOL
Trimethylhydroxymethylsilane
TriMethylsilylMethanol
Methanol, 1-(trimethylsilyl)-
methoxytrimethylsilane
EINECS 221-746-5
trimethylsilanyl-methanol
Hydroxymethyltrimethylsilane
(Hydroxymethyl)trimethylsilane
MFCD00004596
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