LY393615

Modify Date: 2024-01-26 21:34:50

LY393615 structure	Common Name	LY393615
	CAS Number	325819-97-4	Molecular Weight	381.89
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₆ClF₂NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LY393615

LY393615 (NCC1048) is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research[1].

Name	LY393615

Description	LY393615 (NCC1048) is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
Target	P/Q-type calcium channel:4 μM (IC50)
References	[1]. O'Neill MJ, et.al. LY393615, a novel neuronal Ca(2+) and Na(+) channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischemia. Brain Res. 2001 Jan 5;888(1):138-149.

Molecular Formula	C₂₁H₂₆ClF₂NO
Molecular Weight	381.89

LY393615

Use of LY393615

Names

LY393615 Biological Activity

Chemical & Physical Properties