(2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(2H31)hexadecanoyloxy]propyl (2H31)hexadecanoate

Modify Date: 2024-01-09 12:51:49

(2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(2H31)hexadecanoyloxy]propyl (2H31)hexadecanoate Structure
(2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(2H31)hexadecanoyloxy]propyl (2H31)hexadecanoate structure
Common Name (2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(2H31)hexadecanoyloxy]propyl (2H31)hexadecanoate
CAS Number 326495-42-5 Molecular Weight 754.341
Density 1.0±0.1 g/cm3 Boiling Point 723.6±70.0 °C at 760 mmHg
Molecular Formula C37H12D62NO8P Melting Point N/A
MSDS N/A Flash Point 391.4±35.7 °C

 Use of (2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(2H31)hexadecanoyloxy]propyl (2H31)hexadecanoate


1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d62 is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is an endogenous metabolite.

 Names

Name (2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(2H31)hexadecanoyloxy]propyl (2H31)hexadecanoate
Synonym More Synonyms

  Biological Activity

Description 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d62 is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is an endogenous metabolite.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 723.6±70.0 °C at 760 mmHg
Molecular Formula C37H12D62NO8P
Molecular Weight 754.341
Flash Point 391.4±35.7 °C
Exact Mass 753.904358
LogP 13.70
Vapour Pressure 0.0±5.1 mmHg at 25°C
Index of Refraction 1.474

 Synonyms

Hexadecanoic-d acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
(2R)-3-{[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy}-2-[(H)hexadecanoyloxy]propyl (H)hexadecanoate