4-Desacetylvinblastine
4-Desacetylvinblastine structure
|
Common Name | 4-Desacetylvinblastine | ||
|---|---|---|---|---|
| CAS Number | 3352-69-0 | Molecular Weight | 768.93700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H56N4O8 | Melting Point | 189-191℃ | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-Desacetylvinblastine4-Desacetylvinblastine is a a pro-drug of Vinblastine. An anti-tumor agent used in the treatment of prostate cancer. |
| Name | 4-O-des-acetyl vinblastine |
|---|---|
| Synonym | More Synonyms |
| Melting Point | 189-191℃ |
|---|---|
| Molecular Formula | C44H56N4O8 |
| Molecular Weight | 768.93700 |
| Exact Mass | 768.41000 |
| PSA | 148.03000 |
| LogP | 3.36090 |
|
Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.
Cancer Chemother. Pharmacol. 32(4) , 286-92, (1993) We have developed and validated a selective analytical procedure, based on ion-exchange normal-phase liquid chromatography with fluorescence detection and liquid-liquid extraction, for the analysis of... |
|
|
Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice.
J. Pharmacol. Exp. Ther. 241(2) , 695-703, (1987) The monoclonal antibody-vinca alkaloid conjugate, KS1/4-DAVLB (LY256787), and free 4-desacetylvinblastine (DAVLB) were administered i.v. to male athymic nude mice bearing P3/UCLA human lung adenocarci... |
|
|
Quantitation of human anti-mouse antibody in serum by flow cytometry.
Cytometry 13(3) , 275-81, (1992) Clinical investigations utilizing murine monoclonal antibodies require techniques for the detection of the human anti-mouse antibody (HAMA) response in patient serum. We report here a flow cytometric ... |
| 4-desacetyl vinblastine |