SMIFH2

Modify Date: 2024-01-11 19:46:49

SMIFH2 Structure
SMIFH2 structure
Common Name SMIFH2
CAS Number 340316-62-3 Molecular Weight 377.21300
Density N/A Boiling Point N/A
Molecular Formula C15H9BrN2O3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of SMIFH2


SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM.

 Names

Name (5E)-1-(3-Bromophenyl)-5-(2-furylmethylene)-2-thioxodihydro-4,6(1 H,5H)-pyrimidinedione
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C15H9BrN2O3S
Molecular Weight 377.21300
Exact Mass 375.95200
PSA 98.13000
LogP 3.21430
Storage condition 2-8°C

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII

 Articles1

More Articles
Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2.

J. Biol. Chem. 288(22) , 15466-73, (2013)

Myofibroblast differentiation plays a critical role in wound healing and in the pathogenesis of fibrosis. We have previously shown that myofibroblast differentiation is mediated by the activity of ser...

 Synonyms

1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
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