Kynurenine

Modify Date: 2024-01-11 15:30:11

Kynurenine Structure
Kynurenine structure
Common Name Kynurenine
CAS Number 343-65-7 Molecular Weight 208.214
Density 1.3±0.1 g/cm3 Boiling Point 466.6±45.0 °C at 760 mmHg
Molecular Formula C10H12N2O3 Melting Point ~235 °C (dec.)
MSDS USA Flash Point 236.0±28.7 °C

 Use of Kynurenine


Kynurenine is a metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway. It causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels..

 Names

Name kynurenine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 466.6±45.0 °C at 760 mmHg
Melting Point ~235 °C (dec.)
Molecular Formula C10H12N2O3
Molecular Weight 208.214
Flash Point 236.0±28.7 °C
Exact Mass 208.084793
PSA 106.41000
LogP 1.09
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.626

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922509090

 Synthetic Route

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles109

More Articles
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives on these processes.

J. Nutr. 145(1) , 87-95, (2015)

The use of oral contraceptives (OCs) has been associated with low plasma pyridoxal 5'-phosphate (PLP). The functional consequences are unclear.To determine whether functional vitamin B-6 insufficiency...

Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.

J. Chromatogr. A. 562(1-2) , 125-38, (1991)

Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease...

Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.

Brain 115 ( Pt 5) , 1249-73, (1992)

Neurological dysfunction, seizures and brain atrophy occur in a broad spectrum of acute and chronic neurological diseases. In certain instances, over-stimulation of N-methyl-D-aspartate receptors has ...

 Synonyms

DL-Kynurenin
rac Kynurenine-13C2,15N
EINECS 206-445-9
Alanine, 3-anthraniloyl-, DL-
DL-2-Amino-3-(2-aminobenzoyl)propionic acid
Alanine, 3-anthraniloyl-
Kynurenin
(±)-Kynurenine
3-anthraniloyl-alanine
3-Anthraniloylalanine
Benzenebutanoic acid, α,2-diamino-γ-oxo-
MFCD00025194
DL-kynurenine
Alanine,3-anthraniloyl
racKynurenine
Quinurenine
3-Anthraniloyl-DL-alanine
Kynurenine
2-Amino-4-(2-amino-phenyl)-4-oxo-buttersaeure
α,2-diamino-γ-oxo-Benzenebutanoic acid
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
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