N1-Acetylspermidine hydrochloride

Modify Date: 2024-01-05 19:55:40

N1-Acetylspermidine hydrochloride structure	Common Name	N1-Acetylspermidine hydrochloride
	CAS Number	34450-16-3	Molecular Weight	223.74300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₂₃Cl₂N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N1-Acetylspermidine hydrochloride

N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1-acetylspermine is the substrate for the polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1-acetylspermidine shows cleavage efficiency at apurinic sites in DNA[1][2][3].

Name	N1-acetylspermidine dihydrochloride
Synonym	More Synonyms

Description	N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1-acetylspermine is the substrate for the polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1-acetylspermidine shows cleavage efficiency at apurinic sites in DNA[1][2][3].
Related Catalog	Research Areas >> Cancer
References	[1]. Royo M, et al. Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate. Biochemistry. 2005 May 10;44(18):7079-84. [2]. Takenoshita S, et al. Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. Cancer Res. 1984 Feb;44(2):845-7. [3]. Haukanes BI, et al. Action of spermidine, N1-acetylspermidine, and N8-acetylspermidine at apurinic sites in DNA.

Description

Related Catalog

Research Areas >> Cancer

References

[1]. Royo M, et al. Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate. Biochemistry. 2005 May 10;44(18):7079-84.

[2]. Takenoshita S, et al. Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. Cancer Res. 1984 Feb;44(2):845-7.

[3]. Haukanes BI, et al. Action of spermidine, N1-acetylspermidine, and N8-acetylspermidine at apurinic sites in DNA.