1-(2-Pyridinyl)piperazine
1-(2-Pyridinyl)piperazine structure
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Common Name | 1-(2-Pyridinyl)piperazine | ||
|---|---|---|---|---|
| CAS Number | 34803-66-2 | Molecular Weight | 163.22 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 314.4±22.0 °C at 760 mmHg | |
| Molecular Formula | C9H13N3 | Melting Point | 92-94 | |
| MSDS | Chinese USA | Flash Point | 143.9±22.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 1-(2-Pyridinyl)piperazine1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| Name | 1-pyridin-2-ylpiperazine |
|---|---|
| Synonym | More Synonyms |
| Description | 1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | |
| In Vitro | 1-(2-Pyridyl)piperazine 是一种选择性的 α2-肾上腺素能受体拮抗剂。它显示出同情活动。它也是 Azaperone 的代谢产物。 |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 314.4±22.0 °C at 760 mmHg |
| Melting Point | 92-94 |
| Molecular Formula | C9H13N3 |
| Molecular Weight | 163.22 |
| Flash Point | 143.9±22.3 °C |
| Exact Mass | 163.110947 |
| PSA | 28.16000 |
| LogP | 0.19 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.547 |
| Storage condition | Flammables area |
| Water Solubility | >500 g/L (20 ºC) |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | 2735 |
| WGK Germany | 3 |
| Packaging Group | II |
| Hazard Class | 8 |
| HS Code | 2933990090 |
|
~54%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; CHEMON INC. Patent: WO2008/153325 A1, 2008 ; Location in patent: Page/Page column 43 ; |
|
~97%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: BIOENERGENIX; MCCALL, John, M.; MCKEARN, John; ROMERO, Donnal, L.; CLAIR, Michael Patent: WO2011/28947 A2, 2011 ; Location in patent: Page/Page column 50; 51 ; WO 2011/028947 A1 |
|
~77%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: Brenner, Eric; Schneider, Raphael; Fort, Yves Tetrahedron Letters, 2000 , vol. 41, # 16 p. 2881 - 2884 |
|
~76%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: Tetrahedron, , vol. 58, # 34 p. 6913 - 6924 |
|
~91%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: Brenner, Eric; Schneider, Raphael; Fort, Yves Tetrahedron, 1999 , vol. 55, # 44 p. 12829 - 12842 |
|
~%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: Tetrahedron, , vol. 55, # 44 p. 12829 - 12842 |
|
~%
1-(2-Pyridinyl)... CAS#:34803-66-2 |
| Literature: Journal of Organic Chemistry, , vol. 18, p. 1484,1487 |
| Precursor 5 | |
|---|---|
| DownStream 10 | |
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CAS#:100-61-8| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Pharmacological evidence for the involvement of 1-(2-pyridinyl)-piperazine (1-PmP) in the interaction of buspirone or gepirone with noradrenergic systems.
Eur. J. Pharmacol. 134(1) , 113-6, (1987) We investigated in mice the effects of one of the principal metabolites of buspirone and gepirone, 1-(2-pyridinyl)-piperazine (1-PmP), on hypothermia and reduced locomotion induced by clonidine (0.25 ... |
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6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats.
Drug Metab. Dispos. 35(8) , 1387-92, (2007) The pharmacokinetics and in vivo potency of 6-hydroxybuspirone (6-OH-buspirone), a major metabolite of buspirone, were investigated. The plasma clearance (47.3 +/- 3.5 ml/min/kg), volume of distributi... |
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New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines.
Bioorg. Med. Chem. 16 , 8737-44, (2008) Six new synthetic bile acid derivatives were synthesized and tested in vitro against various human cancer cells (glioblastoma multiforme (GBM), multiple myeloma (KMS-11), and colonic carcinoma (HCT-11... |
| 2-(1-Piperazinyl)pyridine |
| 1-(pyridin-2-yl)piperazine |
| 2-Piperazinopyridine |
| 1-(2-Pyridinyl)piperazine |
| Piperazine, 1-(2-pyridinyl)- |
| MFCD00006216 |
| EINECS 252-220-3 |
| 2-pyridylpiperazine |
| 1-(2-Pyridyl)Piperazine |
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- Product Name: 1-(2-Pyridinyl)piperazine
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- Product Name: 1-(2-Pyridyl)piperazine
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