aldophosphamide

Modify Date: 2024-01-06 11:19:27

aldophosphamide structure	Common Name	aldophosphamide
	CAS Number	35144-64-0	Molecular Weight	277.09
	Density	1.347g/cm3	Boiling Point	388.9ºC at 760 mmHg
	Molecular Formula	C₇H₁₅Cl₂N₂O₃P	Melting Point	N/A
	MSDS	N/A	Flash Point	189ºC

Use of aldophosphamide

Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research[1].

Name	3-[amino-[bis(2-chloroethyl)amino]phosphoryl]oxypropanal
Synonym	More Synonyms

Description	Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Fenselau C, et al. Identification of aldophosphamide as a metabolite of cyclophosphamide in vitro and in vivo in humans. Cancer Res. 1977 Aug;37(8 Pt 1):2538-43.

Density	1.347g/cm3
Boiling Point	388.9ºC at 760 mmHg
Molecular Formula	C₇H₁₅Cl₂N₂O₃P
Molecular Weight	277.09
Flash Point	189ºC
Exact Mass	276.02000
PSA	82.44000
LogP	2.13870
Index of Refraction	1.497

Precursor 8
CAS#:39800-29-8 Phosphorodiamid... CAS#:39800-16-3 4-Hydroperoxy c... CAS#:52336-54-6 Alcophosphamide CAS#:61903-29-5 (2R,4R)-2-(bis(...
CAS#:84210-72-0 cis-Mosfosfamide CAS#:19767-45-4 MESNA CAS#:61903-30-8 (R,S)-4-Hydroxy... CAS#:50-18-0 Cyclophosphamide
DownStream 4
CAS#:61903-29-5 (2R,4R)-2-(bis(... CAS#:61903-30-8 (R,S)-4-Hydroxy... CAS#:10159-53-2 Phosphoramide m... CAS#:65263-76-5 4-[amino-[bis(2...