5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Modify Date: 2024-01-02 10:35:40

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid structure
Common Name 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
CAS Number 356068-93-4 Molecular Weight 300.284
Density 1.5±0.1 g/cm3 Boiling Point 588.4±50.0 °C at 760 mmHg
Molecular Formula C16H13FN2O3 Melting Point N/A
MSDS N/A Flash Point 309.7±30.1 °C

 Names

Name 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 588.4±50.0 °C at 760 mmHg
Molecular Formula C16H13FN2O3
Molecular Weight 300.284
Flash Point 309.7±30.1 °C
Exact Mass 300.091034
PSA 82.19000
LogP 3.06
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.690
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~95%

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure

5-((Z)-(5-Fluor...

CAS#:356068-93-4

Literature: SCINOPHARM TAIWAN, LTD.; Henscheke, Julian P.; Chen, Yung-Fa Patent: US2013/190512 A1, 2013 ; Location in patent: Paragraph 0088 ;

~80%

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure

5-((Z)-(5-Fluor...

CAS#:356068-93-4

Literature: Tang, Peng Cho; Miller, Todd A.; Li, Xiaoyuan; Sun, Li; Wei, Chung Chen; Shirazian, Shahrzad; Liang, Congxin; Vojkovsky, Tomas; Nematalla, Asaad S.; Hawley, Michael Patent: US2002/156292 A1, 2002 ;

~97%

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure

5-((Z)-(5-Fluor...

CAS#:356068-93-4

Literature: SCINOPHARM TAIWAN, LTD.; Henscheke, Julian P.; Chen, Yung-Fa Patent: US2013/190512 A1, 2013 ; Location in patent: Paragraph 0087 ;

~%

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure

5-((Z)-(5-Fluor...

CAS#:356068-93-4

Literature: WO2012/58780 A1, ;

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5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure

5-((Z)-(5-Fluor...

CAS#:356068-93-4

Literature: Journal of Medicinal Chemistry, , vol. 46, # 7 p. 1116 - 1119

~%

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure

5-((Z)-(5-Fluor...

CAS#:356068-93-4

Literature: Journal of Medicinal Chemistry, , vol. 46, # 7 p. 1116 - 1119

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
1H-Pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-