5-Bromo-2,4-dichloropyrimidine structure
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Common Name | 5-Bromo-2,4-dichloropyrimidine | ||
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CAS Number | 36082-50-5 | Molecular Weight | 227.874 | |
Density | 2.0±0.1 g/cm3 | Boiling Point | 287.5±20.0 °C at 760 mmHg | |
Molecular Formula | C4HBrCl2N2 | Melting Point | 29-30 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 127.7±21.8 °C | |
Symbol |
GHS05, GHS06 |
Signal Word | Danger |
Name | 5-Bromo-2,4-dichloropyrimidine |
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Synonym | More Synonyms |
Density | 2.0±0.1 g/cm3 |
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Boiling Point | 287.5±20.0 °C at 760 mmHg |
Melting Point | 29-30 °C(lit.) |
Molecular Formula | C4HBrCl2N2 |
Molecular Weight | 227.874 |
Flash Point | 127.7±21.8 °C |
Exact Mass | 225.870010 |
PSA | 25.78000 |
LogP | 2.06 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.605 |
Storage condition | Keep Cold |
Symbol |
GHS05, GHS06 |
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Signal Word | Danger |
Hazard Statements | H301 + H311 + H331-H314-H317 |
Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338-P310 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges |
Hazard Codes | T:Toxic |
Risk Phrases | R23/24/25;R34 |
Safety Phrases | S26-S27-S36/37/39-S45 |
RIDADR | UN 3263 8/PG 2 |
WGK Germany | 3 |
Packaging Group | III |
Hazard Class | 8 |
HS Code | 2933599090 |
~81% 5-Bromo-2,4-dic... CAS#:36082-50-5 |
Literature: PCR, Incorporated Patent: US4299961 A1, 1981 ; |
~% 5-Bromo-2,4-dic... CAS#:36082-50-5 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7169 - 7173,5 |
~% 5-Bromo-2,4-dic... CAS#:36082-50-5 |
Literature: American Chemical Journal, , vol. 33, p. 443 |
Precursor 4 | |
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DownStream 10 | |
HS Code | 2933599090 |
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Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors.
J. Med. Chem. 56(23) , 9683-92, (2013) Abnormal activation or overexpression of Mer receptor tyrosine kinase has been implicated in survival signaling and chemoresistance in many human cancers. Consequently, Mer is a promising novel cancer... |
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Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.
Bioorg. Med. Chem. Lett. 17(22) , 6206-11, (2007) The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented. |
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Synthesis , 861, (2006)
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5-bromo-2,4-dichloropyrimdine |
Pyrimidine, 5-bromo-2,4-dichloro- |
5-Brom-2,4-dichlor-pyrimidin |
5-Bromo-2,4-dichloropyrimidine |
MFCD00127818 |
2,4,4-TRIMETHYLCYCLOPENTANONE |
5-Bromo-2,4-dichloro-pyrimidine |
2,4-Dichloro-5-bromo pyrimidine |
5-Bromo-2,4-dichloror-pyrimidine |