CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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MJ9653000
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CHEMICAL NAME :
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5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-1-decenyl)cyclopentyl)- , (1R-(1-alpha(Z),2-beta(1E,3S*),3-alpha,5-alpha))-
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CAS REGISTRY NUMBER :
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36950-85-3
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LAST UPDATED :
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198910
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C22-H38-O5
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MOLECULAR WEIGHT :
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382.60
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WISWESSER LINE NOTATION :
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L5TJ AQ B6VQ C1U1YQ7 DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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4 mg/kg
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SEX/DURATION :
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female 4-7 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
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REFERENCE :
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PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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40 mg/kg
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SEX/DURATION :
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female 19-20 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - abortion
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REFERENCE :
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PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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10 mg/kg
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SEX/DURATION :
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female 4-7 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - other measures of fertility
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REFERENCE :
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PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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2250 ug/kg
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SEX/DURATION :
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female 4-6 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - other measures of fertility
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REFERENCE :
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NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 238,400,1972
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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100 ug/kg
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SEX/DURATION :
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female 4-6 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - other measures of fertility
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REFERENCE :
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NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 238,400,1972
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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150 ug/kg
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SEX/DURATION :
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female 4-6 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
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REFERENCE :
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NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 238,400,1972
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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2500 ug/kg
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SEX/DURATION :
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female 14 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - abortion
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REFERENCE :
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PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972
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