Heptaminol

Modify Date: 2024-01-06 16:29:35

Heptaminol Structure
Heptaminol structure
Common Name Heptaminol
CAS Number 372-66-7 Molecular Weight 145.24300
Density 0.895g/cm3 Boiling Point 250.1ºC at 760mmHg
Molecular Formula C8H19NO Melting Point N/A
MSDS N/A Flash Point 105.1ºC

 Names

Name 6-amino-2-methylheptan-2-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.895g/cm3
Boiling Point 250.1ºC at 760mmHg
Molecular Formula C8H19NO
Molecular Weight 145.24300
Flash Point 105.1ºC
Exact Mass 145.14700
PSA 46.25000
LogP 1.97510
Appearance of Characters Oily Liquid | Clear colorless
Index of Refraction 1.455-1.457

 MSDS

Name: 6-Amino-2-methyl-2-heptanol 98% Material Safety Data Sheet
Synonym: Heptaminol; 2-Methyl-2-hydroxy-6-aminoheptan
CAS: 372-66-7
Section 1 - Chemical Product MSDS Name:6-Amino-2-methyl-2-heptanol 98% Material Safety Data Sheet
Synonym:Heptaminol; 2-Methyl-2-hydroxy-6-aminoheptan

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
372-66-7 6-Amino-2-methyl-2-heptanol 98.0 206-758-0
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Antidote: None reported.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 372-66-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: oily, colorless
Odor: amine-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 92 - 93 deg C @ 7.00mm Hg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: miscible
Specific Gravity/Density: .8950g/cm3
Molecular Formula: C8H19NO
Molecular Weight:

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stability unknown.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 372-66-7: MJ3230000 LD50/LC50:
Not available.
Carcinogenicity:
6-Amino-2-methyl-2-heptanol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 372-66-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 372-66-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 372-66-7 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MJ3230000
CHEMICAL NAME :
2-Heptanol, 6-amino-2-methyl-
CAS REGISTRY NUMBER :
372-66-7
BEILSTEIN REFERENCE NO. :
1209267
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H19-N-O
MOLECULAR WEIGHT :
145.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 230,142,1957

 Safety Information

Hazard Codes C: Corrosive;
Risk Phrases 34
Safety Phrases 45-36/37/39-26
HS Code 2922199090

 Synthetic Route

~%

Heptaminol Structure

Heptaminol

CAS#:372-66-7

Literature: El Blidi, Lahssen; Nechab, Malek; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2901 - 2903

~%

Heptaminol Structure

Heptaminol

CAS#:372-66-7

Literature: Fujita et al. Ann. Rep. Tanabe pharm. Res.Chem.Abstr., 1959 , vol. 4, # 2 p. 15,19 Ann. Rep. Tanabe pharm. Res.Chem.Abstr., 1960 , p. 8627

~%

Heptaminol Structure

Heptaminol

CAS#:372-66-7

Literature: Doeuvre; Poizat Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1947 , vol. 224, p. 288

~%

Heptaminol Structure

Heptaminol

CAS#:372-66-7

Literature: Doeuvre; Poizat Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1947 , vol. 224, p. 288

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-Methyl-2-hydroxy-6-aminoheptane
6-Amino-2-methyl-2-heptanol
2-amino-6-hydroxy-6-methyl-heptane
EINECS 206-758-0
heptaminol
2-HEPTANOL,6-AMINO-2-METHYL
MFCD00127893