[Hyp3]Bradykinin

Modify Date: 2024-01-09 11:58:06

[Hyp<sup>3</sup>]Bradykinin structure	Common Name	[Hyp<sup>3</sup>]Bradykinin
	CAS Number	37642-65-2	Molecular Weight	1076.208
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₅₀H₇₃N₁₅O₁₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of [Hyp3]Bradykinin

[Hyp3]-Bradykinin, naturally occurring peptide hormone, is a bradykinin receptor agonist. [Hyp3]-Bradykinin interacts with B2-bradykinin receptors and stimulates inositol phosphate production in cultured human fibroblasts[1].

Name	arg-pro-hyp-gly-phe-ser-pro-phe-arg
Synonym	More Synonyms

Description	[Hyp3]-Bradykinin, naturally occurring peptide hormone, is a bradykinin receptor agonist. [Hyp3]-Bradykinin interacts with B2-bradykinin receptors and stimulates inositol phosphate production in cultured human fibroblasts[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Bradykinin Receptor
In Vitro	[Hyp3]-Bradykinin is as active as native Bradykinin in its ability to bind to bovine uterine myometrium and in its potency on the isolated rat uterus[1].
References	[1]. R Dengler, et al. [Hyp3]-bradykinin and [Hyp3]-Lys-bradykinin interact with B2-bradykinin receptors and stimulate inositol phosphate production in cultured human fibroblasts. FEBS Lett. 1990 Mar 12;262(1):111-4.

Density	1.5±0.1 g/cm3
Molecular Formula	C₅₀H₇₃N₁₅O₁₂
Molecular Weight	1076.208
Exact Mass	1075.556274
PSA	434.01000
LogP	-1.09
Index of Refraction	1.700
Storage condition	-20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
RIDADR	NONH for all modes of transport
WGK Germany	3

Bradykinin receptors and their antagonists.

Eur. J. Pharmacol. 348 , 1-10, (1998)

Bradykinin and related kinins act on two receptor types, named B1 and B2. Initially identified in classical bioassays, these receptors have been cloned and characterized in binding assays performed on...

Bradykinin receptor types and B2 subtypes.

Life Sci. 55 , 735-749, (1994)

Bradykinin, desArg9BK, some agonist analogues and several antagonists have been tested in isolated organs in order to identify bradykinin B2 receptor subtypes. The initial pharmacological characteriza...

Isolation and identification of hydroxyproline analogues of bradykinin in human urine.

FEBS Lett. 232 , 252, (1988)

Hydroxyproline (Hyp) analogues of bradykinin and lysyl-bradykinin, in which the third residue of bradykinin, proline, is replaced by hydroxyproline, were isolated from human urine. Their amino acid se...

[Hyp(3)]-bradykinin

N-(Diaminomethylene)-L-ornithyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-N-(diaminomethylene)-L-ornithine

[HYP3]-BRADYKININ (HUMAN) 2ACOH 3H2O

bradykinin,hydroxy-Pro(3)

L-Ornithine, N-(diaminomethylene)-L-ornithyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-N-(diaminomethylene)-

[HYP3]-BRADYKININ

BRADYKININ [HYP3]

[HYP3]-BRADYKININ (HUMAN)

L-Arg-L-Pro-4-Hydroxy-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Phe-L-Arg-OH

Bradykinin[Hyp3]