O,O-diacetyl-4-hydroxyaminoquinoline 1-oxide

MOLECULAR FORMULA :

C13-H13-N2-O4

MOLECULAR WEIGHT :

261.28

WISWESSER LINE NOTATION :

T66 BN EHJ BOV1 EMVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5 mg/kg/2W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

30 mg/kg/4W-I

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Yeast - Saccharomyces cerevisiae

DOSE/DURATION :

50 mg/L

REFERENCE :

IGSBAL Igaku to Seibutsugaku. Medicine and Biology. (c/o Ogato Igaku Kagaku Kenkyusho, 2-3-5 Bakuro-cho, Nihonbashi, Chuo-ku, Tokyo 103, Japan) V.1- 1942- Volume(issue)/page/year: 85,127,1972