4-Methoxy-4-oxobutanoic acid

Modify Date: 2024-01-02 07:50:22

4-Methoxy-4-oxobutanoic acid Structure
4-Methoxy-4-oxobutanoic acid structure
Common Name 4-Methoxy-4-oxobutanoic acid
CAS Number 3878-55-5 Molecular Weight 132.115
Density 1.2±0.1 g/cm3 Boiling Point 259.2±0.0 °C at 760 mmHg
Molecular Formula C5H8O4 Melting Point 54-57 °C(lit.)
MSDS Chinese USA Flash Point 104.5±16.1 °C

 Names

Name monomethyl succinate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 259.2±0.0 °C at 760 mmHg
Melting Point 54-57 °C(lit.)
Molecular Formula C5H8O4
Molecular Weight 132.115
Flash Point 104.5±16.1 °C
Exact Mass 132.042252
PSA 63.60000
LogP -0.21
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.436
Storage condition 2~8°C
Stability Stable. Incompatible with strong oxidizing agents. Combustible.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2917190090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles26

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Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 300(3) , R756-62, (2011)

Recent evidence suggests that an acute increase in the generation of phagocyte-like NADPH-oxidase (Nox)-mediated reactive oxygen species (ROS) may be necessary for glucose-stimulated insulin secretion...

Stimulation of insulin release in vivo by the methyl esters of succinic acid and glutamic acid.

Adv. Exp. Med. Biol. 426 , 231-4, (1997)

Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis.

Am. J. Physiol. Endocrinol. Metab. 283(2) , E302-10, (2002)

Succinic acid methyl esters are potent insulin secretagogues in rat pancreatic islets, but they do not stimulate insulin release in mouse islets. Unlike rat and human islets, mouse islets lack malic e...

 Synonyms

4-Methoxy-4-oxobutanoic acid
mono-Methyl succinate
Butanedioic acid, monomethyl ester
mono-Methyl hydrogen succinate
MFCD00002788
EINECS 223-408-2
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