2'-(o-methyl)-inosine

Modify Date: 2024-01-21 14:17:25

2'-(o-methyl)-inosine structure	Common Name	2'-(o-methyl)-inosine
	CAS Number	3881-21-8	Molecular Weight	282.25
	Density	1.844g/cm3	Boiling Point	669.568ºC at 760 mmHg
	Molecular Formula	C₁₁H₁₄N₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	358.742ºC

Use of 2'-(o-methyl)-inosine

9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-ol (2'-O-methylinosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one
Synonym	More Synonyms

Description	9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-ol (2'-O-methylinosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.844g/cm3
Boiling Point	669.568ºC at 760 mmHg
Molecular Formula	C₁₁H₁₄N₄O₅
Molecular Weight	282.25
Flash Point	358.742ºC
Exact Mass	282.09600
PSA	122.49000
Appearance of Characters	Powder \| White to Off-white
Index of Refraction	1.774
Water Solubility	Slightly soluble in water.