N-acryloxysuccinimide

Modify Date: 2024-01-02 19:55:36

N-acryloxysuccinimide Structure
N-acryloxysuccinimide structure
Common Name N-acryloxysuccinimide
CAS Number 38862-24-7 Molecular Weight 169.135
Density 1.3±0.1 g/cm3 Boiling Point 251.3±23.0 °C at 760 mmHg
Molecular Formula C7H7NO4 Melting Point 69 °C
MSDS USA Flash Point 105.8±22.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of N-acryloxysuccinimide


2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1].

 Names

Name N-Acryloxysuccinimide
Synonym More Synonyms

 N-acryloxysuccinimide Biological Activity

Description 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1].
Related Catalog
References

[1]. Okyem S, et, al. High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates. Bioconjug Chem. 2021 Aug 18;32(8):1753-1762.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 251.3±23.0 °C at 760 mmHg
Melting Point 69 °C
Molecular Formula C7H7NO4
Molecular Weight 169.135
Flash Point 105.8±22.6 °C
Exact Mass 169.037506
PSA 63.68000
LogP -1.21
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.520
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R36/37/38;R40;R48/20/22
Safety Phrases S36
RIDADR NONH for all modes of transport
WGK Germany 2
HS Code 2925190090

 Synthetic Route

~76%

N-acryloxysuccinimide Structure

N-acryloxysucci...

CAS#:38862-24-7

Literature: Bergbreiter, David E.; Osburn, Philip L.; Li, Chunmei Organic Letters, 2002 , vol. 4, # 5 p. 737 - 740

~65%

N-acryloxysuccinimide Structure

N-acryloxysucci...

CAS#:38862-24-7

Literature: Poechlauer, Peter; Hendel, Wolfram Tetrahedron, 1998 , vol. 54, # 14 p. 3489 - 3494

~75%

N-acryloxysuccinimide Structure

N-acryloxysucci...

CAS#:38862-24-7

Literature: Handke, Nadege; Trimaille, Thomas; Luciani, Elsa; Rollet, Marion; Delair, Thierry; Verrier, Bernard; Bertin, Denis; Gigmes, Didier Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 6 p. 1341 - 1350

~%

N-acryloxysuccinimide Structure

N-acryloxysucci...

CAS#:38862-24-7

Literature: DSM Chemie Linz GmbH Patent: US5734064 A1, 1998 ;

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles5

More Articles
A one-step preparation method of monolithic enzyme reactor for highly efficient sample preparation coupled to mass spectrometry-based proteomics studies.

J. Chromatogr. A. 1412 , 75-81, (2015)

Mass spectrometry (MS) coupled to sample preparation and separation techniques has become a primary tool for proteomics studies. However, due to sample complexity, it is often challenging to achieve f...

Differential regeneration of myocardial infarction depending on the progression of disease and the composition of biomimetic hydrogel.

J. Biosci. Bioeng. 118(4) , 461-8, (2014)

Hydrogel has been used for regenerating myocardial infraction (MI) as a delivery vehicle for cells and growth factors. This study showed that injectable hyaluronic acid (HA)-based hydrogels alone woul...

Effect of sustained release of rhBMP-2 from dried and wet hyaluronic acid hydrogel carriers compared with direct dip coating of rhBMP-2 on peri-implant osteogenesis of dental implants in canine mandibles.

J. Craniomaxillofac. Surg. 44 , 116-25, (2016)

Hyaluronic acid (HA) hydrogel has been used as a carrier of recombinant human bone morphogenetic protein (rhBMP)-2 for sustained delivery. To enhance peri-implant osteogenesis, a dried coating of rhBM...

 Synonyms

N-SucciniMidyl Acrylate
1-(Acryloyloxy)pyrrolidine-2,5-dione
N-acryloxysuccinimide
N-Acryloyloxysuccinimide
Acrylic Acid N-Succinimidyl Ester
1-(Acryloyloxy)-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[(1-oxo-2-propen-1-yl)oxy]-
2,5-pyrrolidinedione, 1-[(1-oxo-2-propenyl)oxy]-
2,5-Dioxopyrrolidin-1-yl acrylate
MFCD00078261
1-[(1-Oxo-2-propenyl)oxy]-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-((1-oxo-2-propenyl)oxy)-
Top Suppliers:I want be here



Get all suppliers and price by the below link:

N-acryloxysuccinimide suppliers


Price: ¥77/250mg

Reference only. check more N-acryloxysuccinimide price