3-(2-Chloro-6-fluorophenyl)acrylic acid structure
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Common Name | 3-(2-Chloro-6-fluorophenyl)acrylic acid | ||
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CAS Number | 392-22-3 | Molecular Weight | 200.59400 | |
Density | 1.42g/cm3 | Boiling Point | 312.8ºC at 760mmHg | |
Molecular Formula | C9H6ClFO2 | Melting Point | 165-169 °C(lit.) | |
MSDS | N/A | Flash Point | 143ºC |
Name | 2-chloro-6-fluorocinnamic acid |
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Synonym | More Synonyms |
Density | 1.42g/cm3 |
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Boiling Point | 312.8ºC at 760mmHg |
Melting Point | 165-169 °C(lit.) |
Molecular Formula | C9H6ClFO2 |
Molecular Weight | 200.59400 |
Flash Point | 143ºC |
Exact Mass | 200.00400 |
PSA | 37.30000 |
LogP | 2.57690 |
Index of Refraction | 1.604 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 392-22-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 163 - 165 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Insoluble. Specific Gravity/Density: Molecular Formula: C9H6ClFO2 Molecular Weight: 200.6 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, hydrogen fluoride gas. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 392-22-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Chloro-6-fluorocinnamic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 392-22-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 392-22-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 392-22-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
Hazard Codes | Xi: Irritant; |
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Risk Phrases | R36/37/38 |
Safety Phrases | S26-S37/39 |
WGK Germany | 3 |
HS Code | 2916399090 |
~% 3-(2-Chloro-6-f... CAS#:392-22-3 |
Literature: Saeed, Aamer; Mahesar, Parvez Ali; Zaib, Sumera; Khan, Muhammad Siraj; Matin, Abdul; Shahid, Mohammad; Iqbal, Jamshed European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 43 - 53 |
~% 3-(2-Chloro-6-f... CAS#:392-22-3 |
Literature: Willstaedt Chemische Berichte, 1931 , vol. 64, p. 2688,2692 |
HS Code | 2916399090 |
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Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
2-Chloro-6-fluorocinnamic acid,predominantly trans |
2-Chloro-6-fluorocinnamicacid |
6-Fluor-2-chlor-trans-zimtsaeure |
RARECHEM BK HW 0069 |
MFCD00051582 |
6-fluoro-2-chloro-trans-cinnamic acid |
2-Chloro-6-fluorocinnamic acid |