10-[3-(dimethylamino)propyl]phenothiazin-2-ol

Modify Date: 2024-01-03 15:30:17

10-[3-(dimethylamino)propyl]phenothiazin-2-ol Structure
10-[3-(dimethylamino)propyl]phenothiazin-2-ol structure
Common Name 10-[3-(dimethylamino)propyl]phenothiazin-2-ol
CAS Number 3926-64-5 Molecular Weight 300.41900
Density 1.204g/cm3 Boiling Point 479.4ºC at 760 mmHg
Molecular Formula C17H20N2OS Melting Point N/A
MSDS N/A Flash Point 243.8ºC

 Names

Name 10-[3-(dimethylamino)propyl]phenothiazin-2-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.204g/cm3
Boiling Point 479.4ºC at 760 mmHg
Molecular Formula C17H20N2OS
Molecular Weight 300.41900
Flash Point 243.8ºC
Exact Mass 300.13000
PSA 52.01000
LogP 4.01160
Index of Refraction 1.639

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO7525000
CHEMICAL NAME :
Phenothiazine, 10-(3-(dimethylamino)propyl)-2-hydroxy-
CAS REGISTRY NUMBER :
3926-64-5
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H20-N2-O-S
MOLECULAR WEIGHT :
300.45
WISWESSER LINE NOTATION :
T C666 BN ISJ B3N1&1 EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 4,2425,1965

 Safety Information

HS Code 2934300000

 Synthetic Route

~%

10-[3-(dimethylamino)propyl]phenothiazin-2-ol Structure

10-[3-(dimethyl...

CAS#:3926-64-5

Literature: Huang; Sands Journal of pharmaceutical sciences, 1967 , vol. 56, # 2 p. 259 - 264

~%

10-[3-(dimethylamino)propyl]phenothiazin-2-ol Structure

10-[3-(dimethyl...

CAS#:3926-64-5

Literature: Craig,P.N. et al. Journal of Organic Chemistry, 1960 , vol. 25, p. 944 - 947

~4%

10-[3-(dimethylamino)propyl]phenothiazin-2-ol Structure

10-[3-(dimethyl...

CAS#:3926-64-5

Literature: Epling, Gary A.; Black, Carole; Rawal, Viresh Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 9 p. 1313 - 1316

 Customs

HS Code 2934300000
Summary 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-hydroxypromazine
2-Hydroxy-10(3'-dimethylaminopropyl)phenothiazin
10-(3-dimethylamino-propyl)-10H-phenothiazin-2-ol
Hydroxypromazin
2-Hydroxy-10-(3-(dimethylamino)propyl)phenothiazine
Phenothiazine,10-(3-(dimethylamino)propyl)-2-hydroxy
N-<3-Dimethylamino-propyl>-2-hydroxy-phenothiazin
2-Hydroxypromazin