BIO 8898

Modify Date: 2024-01-06 15:24:54

BIO 8898 Structure
BIO 8898 structure
Common Name BIO 8898
CAS Number 402564-79-8 Molecular Weight 909.145
Density N/A Boiling Point N/A
Molecular Formula C53H64N8O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BIO 8898


BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay.

 Names

Name BIO 8898

 BIO 8898 Biological Activity

Description BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay.
References References 1. Silvian LF, et al. ACS Chem Biol. 2011 Jun 17;6(6):636-47. 2. Ganesan L, et al. Pharmazie. 2012 May;67(5):374-9. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C53H64N8O6
Molecular Weight 909.145
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