DICHLORO(4,5-DIMETHYL-o-PHENYLENE-DIAMMINE)PLATINUM(II)

MOLECULAR FORMULA :

C8-H12-Cl2-N2-Pt

MOLECULAR WEIGHT :

402.21

WISWESSER LINE NOTATION :

ZR BZ D1 E1 &G-PT-G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

283 mg/kg

TOXIC EFFECTS :

Kidney, Ureter, Bladder - other changes Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Bacteria - Salmonella typhimurium

DOSE/DURATION :

10200 nmol/L

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980