1-Chloro-2-methyl-1-oxopropan-2-yl acetate

Modify Date: 2024-01-04 10:13:38

1-Chloro-2-methyl-1-oxopropan-2-yl acetate structure	Common Name	1-Chloro-2-methyl-1-oxopropan-2-yl acetate
	CAS Number	40635-66-3	Molecular Weight	164.587
	Density	1.2±0.1 g/cm3	Boiling Point	178.8±23.0 °C at 760 mmHg
	Molecular Formula	C₆H₉ClO₃	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	68.3±0.0 °C
	Symbol	GHS05	Signal Word	Danger

Name	1-Chlorocarbonyl-1-methylethyl acetate
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	178.8±23.0 °C at 760 mmHg
Molecular Formula	C₆H₉ClO₃
Molecular Weight	164.587
Flash Point	68.3±0.0 °C
Exact Mass	164.024017
PSA	43.37000
LogP	1.25
Vapour Pressure	1.0±0.3 mmHg at 25°C
Index of Refraction	1.435
Storage condition	2-8°C

MSDS(Chinese)

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Supplemental HS	Reacts violently with water.
Precautionary Statements	P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive;
Risk Phrases	R14;R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3265 8/PG 2
WGK Germany	3
Packaging Group	III
Hazard Class	8
HS Code	2918199090

Propanoic acid,...

CAS#:15805-98-8

1-Chloro-2-meth...

CAS#:40635-66-3

Literature: Schirmeister-Tichy, Helga; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Suhadolnik, Robert J.; Pfleiderer, Wolfgang Helvetica Chimica Acta, 1999 , vol. 82, # 4 p. 597 - 613

2-Hydroxyisobut...

CAS#:594-61-6

Acetyl chloride

CAS#:75-36-5

1-Chloro-2-meth...

CAS#:40635-66-3

Literature: Greenberg; Moffatt Journal of the American Chemical Society, 1973 , vol. 95, # 12 p. 4016 - 4025 Title/Abstract Full Text View citing articles Show Details Friary,A. Journal of Heterocyclic Chemistry, 1978 , vol. 15, p. 63 - 64

2-Hydroxyisobut...

CAS#:594-61-6

Ethanoic anhydride

CAS#:108-24-7

1-Chloro-2-meth...

CAS#:40635-66-3

Literature: Kirillov,A.I.; Ivanova,L.F. Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2258 - 2261 Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2241 - 2245

Precursor 4
CAS#:15805-98-8 Propanoic acid,... CAS#:594-61-6 2-Hydroxyisobut... CAS#:75-36-5 Acetyl chloride CAS#:108-24-7 Ethanoic anhydride
DownStream 6
CAS#:40635-67-4 α-Acetoxy-isobu... CAS#:2142-73-6 2',5'-dimethyla... CAS#:7476-41-7 1-Propanone,2-(... CAS#:87064-06-0 (2-methyl-3-oxo...
CAS#:5420-68-8 phenyl 2-acetyl... CAS#:6283-75-6 Propanoic acid,...

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Efficient synthesis of some dichloroalditols: direct regioselective chlorination of some unprotected alditols by 1-chlorocarbonyl-1-methylethyl acetate. Benazza M, et al.

J. Carbohydr. Chem. 13(7) , 967-79, (1994)

Highly diastereoselective synthesis of nucleoside adducts from the carcinogenic benzo[a]pyrene diol epoxide and a computational analysis.

J. Am. Chem. Soc. 129(1) , 68-76, (2007)

A diastereoselective synthesis of the nucleoside adducts corresponding to a cis ring-opening of the carcinogen (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene ...

2-acetoxyisobutyryl chloride (α-acetoxy-isobutyryl chloride)

Acetic acid, 1-chlorocarbonyl-1-methylethyl ester

2-Acetoxyisobutyryl Chloride

1-Chloro-2-methyl-1-oxo-2-propanyl acetate

2-Acetoxy-2-methylpropionyl Chloride

(1-chloro-2-methyl-1-oxopropan-2-yl) acetate

1-Chloro-2-methyl-1-oxopropan-2-yl acetate

Chlorocarbonyl-1-methylethyl acetate

2-Chloro-1,1-dimethyl-2-oxoethyl acetate

Propanoyl chloride, 2-(acetyloxy)-2-methyl-

MFCD00000708

EINECS 255-016-2