Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane]

Modify Date: 2024-01-14 14:13:17

Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane] Structure
Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane] structure
Common Name Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane]
CAS Number 41353-91-7 Molecular Weight 139.195
Density 1.2±0.1 g/cm3 Boiling Point 211.3±13.0 °C at 760 mmHg
Molecular Formula C8H13NO Melting Point N/A
MSDS N/A Flash Point 60.4±22.2 °C

 Names

Name spiro[1-azabicyclo[2.2.2]octane-3,2'-oxirane]
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 211.3±13.0 °C at 760 mmHg
Molecular Formula C8H13NO
Molecular Weight 139.195
Flash Point 60.4±22.2 °C
Exact Mass 139.099716
PSA 15.77000
LogP 0.83
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.564

 Synthetic Route

~93%

Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane] Structure

Spiro[4-azabicy...

CAS#:41353-91-7

Literature: Pierre Fabre Medicament Patent: US2010/105897 A1, 2010 ; Location in patent: Page/Page column 1-2 ;

~52%

Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane] Structure

Spiro[4-azabicy...

CAS#:41353-91-7

Literature: Apotex Pharmachem Inc. Patent: US2008/249312 A1, 2008 ; Location in patent: Page/Page column 2-3 ;

~54%

Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane] Structure

Spiro[4-azabicy...

CAS#:41353-91-7

Literature: APOTEX PHARMACHEM INC.; Stewart, Craig; Johansen, Michael B.; Datta, Probal Kanti; Zhao, Yajun Patent: US2013/274474 A1, 2013 ; Location in patent: Paragraph 0076-0078 ;

 Synonyms

3-methylenequiniclidine epoxide
3-methylenequinuclidine epoxide
Spiro-1-azabicyclo[2.2.2]octan-3-oxirane
Spiro[4-azabicyclo[2.2.2]octane-2,2'-oxirane]
Spiro[1-azabicyclo[2.2.2]octane-3,2'-oxirane]
spiro[1-aza-bicyclo[2.2.2]octane-3,2'-oxirane]
3-methylenequinuclidine oxide