Piperazine,1-(2-benzofuranylcarbonyl)-4- (phenylmethyl)-,monohydrochloride

Modify Date: 2024-02-03 17:58:05

Piperazine,1-(2-benzofuranylcarbonyl)-4- (phenylmethyl)-,monohydrochloride Structure
Piperazine,1-(2-benzofuranylcarbonyl)-4- (phenylmethyl)-,monohydrochloride structure
Common Name Piperazine,1-(2-benzofuranylcarbonyl)-4- (phenylmethyl)-,monohydrochloride
CAS Number 41716-84-1 Molecular Weight 356.84600
Density N/A Boiling Point 477.5ºC at 760 mmHg
Molecular Formula C20H21ClN2O2 Melting Point N/A
MSDS N/A Flash Point 242.6ºC

 Names

Name 1-benzofuran-2-yl-(4-benzylpiperazin-1-yl)methanone,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 477.5ºC at 760 mmHg
Molecular Formula C20H21ClN2O2
Molecular Weight 356.84600
Flash Point 242.6ºC
Exact Mass 356.12900
PSA 36.69000
LogP 4.06860

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK8220500
CHEMICAL NAME :
Piperazine, 1-(2-benzofuranylcarbonyl)-4-(phenylmethyl)-, monohydrochloride
CAS REGISTRY NUMBER :
41716-84-1
LAST UPDATED :
198812
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H20-N2-O2.Cl-H
MOLECULAR WEIGHT :
356.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2530 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
720 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
48500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979

 Synonyms

Befuraline HCl
Befuraline hydrochloride
DIV 154