3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine

Modify Date: 2024-02-02 18:38:05

3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine Structure
3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine structure
Common Name 3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
CAS Number 41945-37-3 Molecular Weight 226.07300
Density 1.67g/cm3 Boiling Point N/A
Molecular Formula C8H8BrN3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.67g/cm3
Molecular Formula C8H8BrN3
Molecular Weight 226.07300
Exact Mass 224.99000
PSA 30.19000
LogP 2.10860
Index of Refraction 1.687

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR0720000
CHEMICAL NAME :
Pyrazolo(1,5-a)pyrimidine, 3-bromo-5,7-dimethyl-
CAS REGISTRY NUMBER :
41945-37-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-Br-N3
MOLECULAR WEIGHT :
226.10
WISWESSER LINE NOTATION :
T56 ANN FNJ DE G1 I1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1346 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,386,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
458 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,386,1977

 Synthetic Route

~57%

3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine Structure

3-Bromo-5,7-dim...

CAS#:41945-37-3

Literature: ICN Pharmaceuticals, Inc. Patent: US4093617 A1, 1978 ; US 4093617 A

 Synonyms

3-Brom-5,7-dimethyl-pyrazolo<1,5-a>pyrimidin
Pyrazolo(1,5-a)pyrimidine,3-bromo-5,7-dimethyl
3-bromo5,7-dimethylpyrazolo[1,5-a]pyrimidine