SW-083688
Modify Date: 2024-04-02 19:43:29
SW-083688 structure
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Common Name | SW-083688 | ||
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| CAS Number | 422281-45-6 | Molecular Weight | 455.529 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H25N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SW-083688SW-083688 (SW083688) is a potent, highly selective TAOK2 (Thousand-And-One Kinase 2, MAP3K17) inhibitor with IC50 of 1.3 uM; increases the abundance of p62 and inhibits autophagy; TAOK2 is an activator of p38 MAP kinase cascade that is up-regulated in response to environmental stresses, and a potential cancer therapeutic target. |
| Name | SW-083688 |
|---|
| Description | SW-083688 (SW083688) is a potent, highly selective TAOK2 (Thousand-And-One Kinase 2, MAP3K17) inhibitor with IC50 of 1.3 uM; increases the abundance of p62 and inhibits autophagy; TAOK2 is an activator of p38 MAP kinase cascade that is up-regulated in response to environmental stresses, and a potential cancer therapeutic target. |
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| References | References 1. Piala AT, et al. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3923-7. View Related Products by Target MEKK (MAP3K) |
| Molecular Formula | C23H25N3O5S |
|---|---|
| Molecular Weight | 455.529 |