(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol

Modify Date: 2024-01-08 06:01:56

(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol Structure
(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol structure
Common Name (5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol
CAS Number 424803-19-0 Molecular Weight 310.19200
Density 1.42g/cm3 Boiling Point 296.4ºC at 760 mmHg
Molecular Formula C13H8F6O2 Melting Point 110ºC
MSDS N/A Flash Point 133.1ºC

 Names

Name [5-[3,5-bis(trifluoromethyl)phenyl]furan-2-yl]methanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.42g/cm3
Boiling Point 296.4ºC at 760 mmHg
Melting Point 110ºC
Molecular Formula C13H8F6O2
Molecular Weight 310.19200
Flash Point 133.1ºC
Exact Mass 310.04300
PSA 33.37000
LogP 4.47650
Index of Refraction 1.457

 MSDS

Name: {5-[3 5-Di(Trifluoromethyl)phenyl]-2-furyl}methanol Material Safety Data Sheet
Synonym: None Known
CAS: 424803-19-0
Section 1 - Chemical Product MSDS Name:{5-[3 5-Di(Trifluoromethyl)phenyl]-2-furyl}methanol Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
424803-19-0 {5-[3,5-Di(Trifluoromethyl)phenyl]-2-f 97+ unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 424803-19-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: pale-yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 110-113 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C13H8F6O2
Molecular Weight: 310.192

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation, excess heat, direct sunlight., moisture, high humidity.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen fluoride gas, fluorine.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 424803-19-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
{5-[3,5-Di(Trifluoromethyl)phenyl]-2-furyl}methanol - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 22 Do not breathe dust.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 424803-19-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 424803-19-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 424803-19-0 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

HS Code 2932190090

 Synthetic Route

~85%

(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol Structure

(5-(3,5-Bis(tri...

CAS#:424803-19-0

Literature: Kasai, Shizuo; Kamaura, Masahiro; Cho, Nobuo Patent: US2011/251187 A1, 2011 ; Location in patent: Page/Page column 54-55 ;

~63%

(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol Structure

(5-(3,5-Bis(tri...

CAS#:424803-19-0

Detail
Literature: Roger, Julien; Pozgan, Franc; Doucet, Henri Advanced Synthesis and Catalysis, 2010 , vol. 352, # 4 p. 696 - 710

~%

(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol Structure

(5-(3,5-Bis(tri...

CAS#:424803-19-0

Literature: Takeda Pharmaceutical Company Limited Patent: EP2295406 A1, 2011 ;

~%

(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)methanol Structure

(5-(3,5-Bis(tri...

CAS#:424803-19-0

Literature: Takeda Pharmaceutical Company Limited Patent: EP2295406 A1, 2011 ;

 Customs

HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

MFCD00052573