Uridine diphosphate glucuronic acid ammonium

Modify Date: 2024-01-02 11:34:40

Uridine diphosphate glucuronic acid ammonium Structure
Uridine diphosphate glucuronic acid ammonium structure
Common Name Uridine diphosphate glucuronic acid ammonium
CAS Number 43195-60-4 Molecular Weight 597.31600
Density N/A Boiling Point N/A
Molecular Formula C15H25N3O18P2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Uridine diphosphate glucuronic acid ammonium


Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1].

 Names

Name azane,(2S,3S,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonym More Synonyms

  Biological Activity

Description Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Annika J E Borg, et al. Mechanistic characterization of UDP-glucuronic acid 4-epimerase. FEBS J. 2021 Feb;288(4):1163-1178.

[2]. DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701.

 Chemical & Physical Properties

Molecular Formula C15H25N3O18P2
Molecular Weight 597.31600
Exact Mass 597.06100
PSA 337.18000
Storage condition 20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xi
RIDADR NONH for all modes of transport

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 Synonyms

UDP-GlcA
Uridine 5 inverted exclamation marka-diphosphoglucuronic acid ammonium salt
Uridine-diphosphate-glucuronic acid ammonium salt