TKN1

Modify Date: 2024-01-22 18:09:38

TKN1 Structure
TKN1 structure
Common Name TKN1
CAS Number 432533-28-3 Molecular Weight 285.338
Density 1.2±0.1 g/cm3 Boiling Point 361.7±42.0 °C at 760 mmHg
Molecular Formula C17H19NO3 Melting Point N/A
MSDS N/A Flash Point 172.6±27.9 °C

 Use of TKN1


A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.

 Names

Name N-(2-Hydroxy-5-isopropylphenyl)-2-methoxybenzamide
Synonym More Synonyms

 TKN1 Biological Activity

Description A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.
References References 1. Luo Q, et al. Nat Commun. 2017 Aug 29;8(1):378. View Related Products by Target Potassium Channel

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 361.7±42.0 °C at 760 mmHg
Molecular Formula C17H19NO3
Molecular Weight 285.338
Flash Point 172.6±27.9 °C
Exact Mass 285.136505
LogP 3.69
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.611

 Synonyms

Benzamide, N-[2-hydroxy-5-(1-methylethyl)phenyl]-2-methoxy-
N-(2-Hydroxy-5-isopropylphenyl)-2-methoxybenzamide