3’-O-Levulinyl-2’-deoxyadenosine

Modify Date: 2024-01-09 13:32:25

3’-O-Levulinyl-2’-deoxyadenosine Structure
3’-O-Levulinyl-2’-deoxyadenosine structure
Common Name 3’-O-Levulinyl-2’-deoxyadenosine
CAS Number 440327-45-7 Molecular Weight 349.34
Density 1.6±0.1 g/cm3 Boiling Point 640.7±65.0 °C at 760 mmHg
Molecular Formula C15H19N5O5 Melting Point N/A
MSDS N/A Flash Point 341.3±34.3 °C

 Use of 3’-O-Levulinyl-2’-deoxyadenosine


3’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-Deoxy-3'-O-(4-oxopentanoyl)adenosine
Synonym More Synonyms

 3’-O-Levulinyl-2’-deoxyadenosine Biological Activity

Description 3’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 640.7±65.0 °C at 760 mmHg
Molecular Formula C15H19N5O5
Molecular Weight 349.34
Flash Point 341.3±34.3 °C
Exact Mass 349.138611
LogP -0.51
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.716

 Synonyms

Adenosine, 2'-deoxy-3'-O-(1,4-dioxopentyl)-
2'-Deoxy-3'-O-(4-oxopentanoyl)adenosine