2'-O-MOE-N2-ibu-rG

Modify Date: 2024-01-10 16:35:26

2'-O-MOE-N2-ibu-rG structure	Common Name	2'-O-MOE-N2-ibu-rG
	CAS Number	440327-50-4	Molecular Weight	411.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₅N₅O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-O-MOE-N2-ibu-rG

N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
Synonym	More Synonyms

Description	N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Molecular Formula	C₁₇H₂₅N₅O₇
Molecular Weight	411.41
Exact Mass	411.17500
PSA	164.57000
LogP	0.05810

Guanosine,2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)

2'-O-MOE-N2-ibu-rG

2'-O-MOE-N2-ibu-rG

Use of 2'-O-MOE-N2-ibu-rG

Names

2'-O-MOE-N2-ibu-rG Biological Activity

Chemical & Physical Properties

Synonyms