Benzylboronic acid

Modify Date: 2024-01-04 12:42:12

Benzylboronic acid Structure
Benzylboronic acid structure
Common Name Benzylboronic acid
CAS Number 4463-42-7 Molecular Weight 135.956
Density 1.1±0.1 g/cm3 Boiling Point 296.5±33.0 °C at 760 mmHg
Molecular Formula C7H9BO2 Melting Point 110-111°C
MSDS N/A Flash Point 133.1±25.4 °C

 Names

Name Benzylboronic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 296.5±33.0 °C at 760 mmHg
Melting Point 110-111°C
Molecular Formula C7H9BO2
Molecular Weight 135.956
Flash Point 133.1±25.4 °C
Exact Mass 136.069565
PSA 40.46000
LogP 1.61
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.526

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: Benzylboronic acid
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Benzylboronic acid
CAS number:4463-42-7

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, under −20◦C.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C7H9BO2
Molecular weight:136.0

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
HS Code 2931900090

 Synthetic Route

~60%

Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Pintaric; Laza; Olivero; Dunach Tetrahedron Letters, 2004 , vol. 45, # 43 p. 8031 - 8033

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Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Johnson; Van Campen; Grummitt Journal of the American Chemical Society, 1938 , vol. 60, p. 113

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Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Priestley; De Lucca, Indawati; Ghavimi, Bahman; Erickson-Viitanen, Susan; Decicco, Carl P. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 21 p. 3199 - 3202

~%

Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Gmelin Handbook: B: B-Verb.9, 5.2.6, page 205 - 215

~%

Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Matteson, Donald S.; Hiscox, William C.; Fabry-Asztalos, Levente; Kim, Gyung-Youn; Siems III, William F. Organometallics, 2001 , vol. 20, # 13 p. 2920 - 2923

~%

Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Priestley; De Lucca, Indawati; Ghavimi, Bahman; Erickson-Viitanen, Susan; Decicco, Carl P. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 21 p. 3199 - 3202

~%

Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Gmelin Handbook: B: B-Verb.9, 5.3.3, page 238 - 244 Full Text Show Details Hoffmann, A. K.; Groszos, St. J. Patent: US2882317 , 1959 ; C.A., 1959 , p. 16062

~%

Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Krause Patent: DE371467 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1451

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Benzylboronic acid Structure

Benzylboronic acid

CAS#:4463-42-7

Literature: Khotinsky; Melamed Chemische Berichte, 1909 , vol. 42, p. 3095

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Synonyms

phenylboric acid
phenylmethyl-1-boronic acid
Boronic acid, B-(phenylmethyl)-
Benzylboronic acid
benzylboric acid
MFCD01114673
benzyl-dihydroxy-borane
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