CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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BQ4375000
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CHEMICAL NAME :
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Ammonium, ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-phenylbe nzylidene)- 2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, sodium salt
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CAS REGISTRY NUMBER :
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4680-78-8
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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13
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MOLECULAR FORMULA :
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C37-H36-N2-O6-S2.Na
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MOLECULAR WEIGHT :
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691.86
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WISWESSER LINE NOTATION :
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L6Y DYJ AUYR&R DN2&1R CSWQ&& DUK2&1R CSWQ &Q &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD - Lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>3 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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100 mg/m3/13W-I
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TOXIC EFFECTS :
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Related to Chronic Data - death
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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660 gm/kg/43W-C
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease
MUTATION DATA
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TYPE OF TEST :
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Mutation in microorganisms
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TEST SYSTEM :
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Bacteria - Salmonella typhimurium
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DOSE/DURATION :
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320 ug/plate
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,21,1981 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,199,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,199,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2189 No. of Facilities: 183 (estimated) No. of Industries: 4 No. of Occupations: 18 No. of Employees: 2742 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2189 No. of Facilities: 400 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 5996 (estimated) No. of Female Employees: 3818 (estimated)
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