Phillyrin structure
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Common Name | Phillyrin | ||
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CAS Number | 487-41-2 | Molecular Weight | 534.552 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 730.4±60.0 °C at 760 mmHg | |
Molecular Formula | C27H34O11 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 395.5±32.9 °C |
Use of PhillyrinPhillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities[1]. |
Name | forsythin |
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Synonym | More Synonyms |
Description | Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities[1]. |
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Related Catalog | |
Target |
CYP1A2; CYP2D1[1] |
In Vitro | Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells[1]. Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes[1]. RT-PCR[1] Cell Line: Human HepG2 hepatocyte cells Concentration: 1 μM; 2.5 μM; 5 μM Incubation Time: 24 hours Result: Reduced FAS and SREBP-1c mRNA expression. |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 730.4±60.0 °C at 760 mmHg |
Molecular Formula | C27H34O11 |
Molecular Weight | 534.552 |
Flash Point | 395.5±32.9 °C |
Exact Mass | 534.210083 |
PSA | 145.53000 |
LogP | 0.08 |
Vapour Pressure | 0.0±2.5 mmHg at 25°C |
Index of Refraction | 1.596 |
Precursor 2 | |
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DownStream 0 |
β-D-Glucopyranoside, 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl |
Pillyrin |
Chionanthin |
4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl β-D-glucopyranoside |
PHILLYRIN |
Phillyroside |
phyllyrin |
[1S-(1a,3aa,4b,6aa)]-4-[4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl-b-D-glucopyranoside |