Dehydroemetine

Modify Date: 2024-01-09 14:28:14

Dehydroemetine Structure
Dehydroemetine structure
Common Name Dehydroemetine
CAS Number 4914-30-1 Molecular Weight 478.62300
Density 1.19g/cm3 Boiling Point 604.7ºC at 760mmHg
Molecular Formula C29H38N2O4 Melting Point 94-96°
MSDS N/A Flash Point 319.5ºC

 Use of Dehydroemetine


Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites[1].

 Names

Name (11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-4,6,7,11b-tetrahydro-1H-benzo[a]quinolizine
Synonym More Synonyms

 Dehydroemetine Biological Activity

Description Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites[1].
Related Catalog
References

[1]. Fouarge M, et al.Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis.J Microencapsul. 1989 Jan-Mar;6(1):29-34.

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 604.7ºC at 760mmHg
Melting Point 94-96°
Molecular Formula C29H38N2O4
Molecular Weight 478.62300
Flash Point 319.5ºC
Exact Mass 478.28300
PSA 52.19000
LogP 5.27430
Index of Refraction 1.606

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JY5095000
CHEMICAL NAME :
Emetine, 2,3-didehydro-
CAS REGISTRY NUMBER :
4914-30-1
LAST UPDATED :
199410
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C29-H38-N2-O4
MOLECULAR WEIGHT :
478.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
68800 ug/kg/24H (Continuous)
REFERENCE :
IMSCE2 IRCS Medical Science. (Lancaster, UK) V.12-14, 1984-86. For publisher information, see MSCREJ. Volume(issue)/page/year: 13,946,1985

 Synonyms

Dehydroemetinum
Dehidroemetina
2,3-didehydro-emetine
2,3-Didehydroemetin
Emetine,2,3-didehydro
10,11,6',7'-tetramethoxy-emet-2-ene
Mebadin
dehydroemetine
BT 436
2-Dehydroemetine
(-)-2,3-Dehydroemetine
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