4-Trifluoromethyl-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester

Modify Date: 2024-01-02 12:24:44

4-Trifluoromethyl-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester Structure
4-Trifluoromethyl-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester structure
Common Name 4-Trifluoromethyl-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester
CAS Number 495415-51-5 Molecular Weight 297.271
Density 1.3±0.1 g/cm3 Boiling Point 347.4±42.0 °C at 760 mmHg
Molecular Formula C12H18F3NO4 Melting Point N/A
MSDS N/A Flash Point 163.9±27.9 °C

 Names

Name 1-[(2-methylpropan-2-yl)oxycarbonyl]-4-(trifluoromethyl)piperidine-4-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 347.4±42.0 °C at 760 mmHg
Molecular Formula C12H18F3NO4
Molecular Weight 297.271
Flash Point 163.9±27.9 °C
Exact Mass 297.118805
PSA 66.84000
LogP 2.29
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.457

 Synthetic Route

~%

4-Trifluoromethyl-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester Structure

4-Trifluorometh...

CAS#:495415-51-5

Literature: GLAXO GROUP LIMITED Patent: WO2004/2490 A2, 2004 ; Location in patent: Page/Page column 22 ;

 Synonyms

4-trifluoromethyl-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester
1,4-Piperidinedicarboxylic acid, 4-(trifluoromethyl)-, 1-(1,1-dimethylethyl) ester
n-boc-4-trifluoromethylpiperidine-4-carboxylic acid
1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-4-(trifluoromethyl)-4-piperidinecarboxylic acid