Phenyl(2-pyridinyl)acetonitrile

Modify Date: 2024-01-06 18:11:20

Phenyl(2-pyridinyl)acetonitrile structure	Common Name	Phenyl(2-pyridinyl)acetonitrile
	CAS Number	5005-36-7	Molecular Weight	194.23
	Density	1.1±0.1 g/cm3	Boiling Point	322.3±27.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₀N₂	Melting Point	83-85ºC
	MSDS	N/A	Flash Point	115.2±8.9 °C

Use of Phenyl(2-pyridinyl)acetonitrile

2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion[1].

Name	2-Phenyl-2-(pyridin-2-yl)acetonitrile
Synonym	More Synonyms

Description	2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion[1].
Related Catalog	Research Areas >> Endocrinology
References	[1]. Gibson MJ, et al. The metabolism of thioamides by the supernatant fraction of rat liver homogenate. J Pharm Pharmacol. 1969 Dec;21:Suppl:195S+.

Density	1.1±0.1 g/cm3
Boiling Point	322.3±27.0 °C at 760 mmHg
Melting Point	83-85ºC
Molecular Formula	C₁₃H₁₀N₂
Molecular Weight	194.23
Flash Point	115.2±8.9 °C
Exact Mass	194.084396
PSA	36.68000
LogP	1.81
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.589
Storage condition	-20°C Freezer

Phenyl(2-pyridinyl)acetonitrile MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36
HS Code	2933399090

2-Chloropyridine

CAS#:109-09-1

Benzyl cyanide

CAS#:140-29-4

~88%

Phenyl(2-pyridi...

CAS#:5005-36-7

Literature: Celgene Corporation Patent: US6359139 B1, 2002 ; Location in patent: Example 1 ;

2-Bromopyridine

CAS#:109-04-6

Benzyl cyanide

CAS#:140-29-4

~71%

Phenyl(2-pyridi...

CAS#:5005-36-7

Literature: Cherng, Yie-Jia Tetrahedron, 2002 , vol. 58, # 24 p. 4931 - 4935

2-Iodopyridine

CAS#:5029-67-4

Benzyl cyanide

CAS#:140-29-4

~68%

Phenyl(2-pyridi...

CAS#:5005-36-7

Literature: Cherng, Yie-Jia Tetrahedron, 2002 , vol. 58, # 24 p. 4931 - 4935

2-Fluoropyridine

CAS#:372-48-5

Benzyl cyanide

CAS#:140-29-4

~66%

Phenyl(2-pyridi...

CAS#:5005-36-7

Literature: Cherng, Yie-Jia Tetrahedron, 2002 , vol. 58, # 24 p. 4931 - 4935

2,6-Dibromopyridine

CAS#:626-05-1

Benzyl cyanide

CAS#:140-29-4

~0%

Phenyl(2-pyridi...

CAS#:5005-36-7

2-bromo-6-(α-cy...

CAS#:84960-28-1

Detail

Literature: Carver, David R.; Greenwood, Thomas D.; Hubbard, James S.; Komin, Andrew P.; Sachdeva, Yesh P.; Wolfe, James F. Journal of Organic Chemistry, 1983 , vol. 48, # 8 p. 1180 - 1185

2-Methoxypyridine

CAS#:1628-89-3

Benzyl cyanide

CAS#:140-29-4

~39%

Phenyl(2-pyridi...

CAS#:5005-36-7

Literature: Yamanaka, Hiroshi; Ohba, Setsuya Heterocycles, 1990 , vol. 31, # 5 p. 895 - 909

2-Bromopyridine

CAS#:109-04-6

Benzyl cyanide

CAS#:140-29-4

2-Benzoylpyridine

CAS#:91-02-1

Phenyl(2-pyridi...

CAS#:5005-36-7

Literature: Hermann, Christine K. F.; Sachdeva, Yesh P.; Wolfe, James F. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1061 - 1065

Precursor 7
CAS#:109-09-1 2-Chloropyridine CAS#:140-29-4 Benzyl cyanide CAS#:109-04-6 2-Bromopyridine CAS#:5029-67-4 2-Iodopyridine
CAS#:372-48-5 2-Fluoropyridine CAS#:626-05-1 2,6-Dibromopyridine CAS#:1628-89-3 2-Methoxypyridine
DownStream 6
CAS#:19395-42-7 2-PHENYL-2-PYRI... CAS#:611-70-1 Isobutyrophenone CAS#:86-21-5 Pheniramine CAS#:7251-52-7 2-Phenyl-2-(2-p...
CAS#:91-02-1 2-Benzoylpyridine CAS#:342403-52-5 [2-hydroxy-2-ph...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%