Rosuvastatin Lactone

Modify Date: 2024-01-02 23:00:18

Rosuvastatin Lactone Structure
Rosuvastatin Lactone structure
 Common Name Rosuvastatin Lactone
CAS Number 503610-43-3 Molecular Weight 463.522
Density 1.4±0.1 g/cm3 Boiling Point 695.0±65.0 °C at 760 mmHg
Molecular Formula C22H26FN3O5S Melting Point 131℃
MSDS N/A Flash Point 374.1±34.3 °C

 Use of Rosuvastatin Lactone


Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor)[1].

 Names

Name Rosuvastatin Lactone
Synonym More Synonyms

 Rosuvastatin Lactone Biological Activity

Description Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor)[1].
Related Catalog
References

[1]. Lee HB, et al. Occurrence and fate of rosuvastatin, rosuvastatin lactone, and atorvastatin in Canadian sewage and surface water samples. Chemosphere. 2009 Nov;77(10):1285-91.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 695.0±65.0 °C at 760 mmHg
Melting Point 131℃
Molecular Formula C22H26FN3O5S
Molecular Weight 463.522
Flash Point 374.1±34.3 °C
Exact Mass 463.157715
PSA 118.07000
LogP 0.42
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.615
Storage condition -20℃

 Synthetic Route

 Synonyms

Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-
RosuvastatinLactone
(3R,5R)-ROSUVASTATIN LACTONE
Rosuvastatin lactone
N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]vinyl}-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide
ROSUVASTATIN-5S-LACTONE
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